Tsung-Ming Lee Selected Research

Nicorandil (SG 75)

1/2018	Nicorandil regulates the macrophage skewing and ameliorates myofibroblasts by inhibition of RhoA/Rho-kinase signalling in infarcted rats.
3/2009	Effect of nicorandil on proteinuria in well controlled hypertensive patients.
4/2008	Effect of ATP-sensitive potassium channel agonists on ventricular remodeling in healed rat infarcts.
12/2007	Effect of pravastatin on sympathetic reinnervation in postinfarcted rats.
3/2007	Effects of pravastatin on ventricular remodeling by activation of myocardial KATP channels in infarcted rats: role of 70-kDa S6 kinase.
12/2006	Effect of pravastatin on left ventricular mass in the two-kidney, one-clip hypertensive rats.
10/2004	Effect of pravastatin on left ventricular mass by activation of myocardial K ATP channels in hypercholesterolemic rabbits.
1/2002	Loss of preconditioning by attenuated activation of myocardial ATP-sensitive potassium channels in elderly patients undergoing coronary angioplasty.

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Tsung-Ming Lee Research Topics

Disease

35	Infarction (Infarctions) 01/2022 - 04/2002
30	Myocardial Infarction 01/2022 - 04/2002
14	Hypertrophy 01/2017 - 12/2003
10	Fibrosis (Cirrhosis) 11/2020 - 09/2006
8	Cardiac Arrhythmias (Arrythmia) 10/2021 - 03/2010
8	Ventricular Remodeling 03/2019 - 09/2006
7	Cardiomegaly (Heart Hypertrophy) 10/2019 - 12/2003
6	Hypertension (High Blood Pressure) 10/2019 - 07/2002
4	Inflammation (Inflammations) 01/2022 - 09/2005
4	Proteinuria 04/2014 - 07/2002
3	Diabetes Mellitus 12/2009 - 02/2003
3	Body Weight (Weight, Body) 12/2006 - 03/2005
3	Hyperlipidemias (Hyperlipidemia) 03/2005 - 10/2002
3	Ischemia 10/2003 - 01/2002
2	Cardiac Sudden Death (Sudden Cardiac Arrest) 01/2020 - 03/2010
2	Left Ventricular Hypertrophy (Ventricular Hypertrophy, Left) 10/2012 - 07/2005
2	Sudden Death 08/2010 - 12/2007
2	Chronic Obstructive Pulmonary Disease (COPD) 03/2009 - 02/2008
2	Hypercholesterolemia 03/2005 - 10/2004
2	Chest Pain (Chest Pains) 02/2003 - 01/2002
2	Myocardial Ischemia (Ischemic Heart Diseases) 02/2003 - 01/2003
2	Coronary Occlusion 01/2003 - 01/2002
1	Cognitive Dysfunction 12/2021
1	Stroke (Strokes) 01/2021
1	Hemorrhage 01/2021
1	Atrial Fibrillation 01/2021

Drug/Important Bio-Agent (IBA)

14	Adenosine Triphosphate (ATP)IBA 01/2018 - 01/2002
14	Pravastatin (Pravachol)FDA LinkGeneric 08/2010 - 07/2002
12	Proteins (Proteins, Gene)FDA Link 01/2022 - 10/2003
10	Nerve Growth Factor (NGF)IBA 01/2022 - 08/2009
9	PotassiumIBA 01/2018 - 01/2003
9	Endothelin-1 (Endothelin 1)IBA 04/2014 - 07/2002
8	Superoxides (Superoxide)IBA 01/2022 - 06/2011
8	Connexin 43 (Connexin43)IBA 10/2021 - 10/2003
8	Messenger RNA (mRNA)IBA 01/2018 - 03/2005
8	Nicorandil (SG 75)IBA 01/2018 - 01/2002
8	salicylhydroxamic acid (SHAM)IBA 07/2015 - 03/2007
7	Norepinephrine (Noradrenaline)FDA LinkGeneric 01/2022 - 12/2007
5	Glyburide (Glibenclamide)FDA LinkGeneric 01/2018 - 01/2003
5	Estradiol (Delestrogen)FDA LinkGeneric 12/2014 - 04/2002
5	Bosentan (Tracleer)FDA Link 04/2014 - 07/2005
5	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 08/2010 - 07/2002
4	butylidenephthalideIBA 11/2020 - 01/2017
4	KATP ChannelsIBA 01/2018 - 09/2005
4	Mevalonic Acid (Mevalonate)IBA 08/2010 - 12/2003
4	Endothelins (Endothelin)IBA 04/2008 - 12/2003
3	InflammasomesIBA 01/2022 - 11/2020
3	Free RadicalsIBA 10/2021 - 12/2002
3	Oxidants (Oxidizing Agents)IBA 03/2019 - 01/2010
3	3-nitrotyrosineIBA 01/2018 - 02/2015
3	LithiumIBA 01/2017 - 12/2014
3	AtrasentanIBA 04/2014 - 04/2008
3	Estrogens (Estrogen)FDA Link 01/2014 - 04/2002
3	Atrial Natriuretic Factor (ANF)IBA 08/2007 - 09/2006
3	Coenzyme A (CoA)IBA 09/2006 - 07/2002
2	Eicosapentaenoic AcidIBA 01/2022 - 01/2020
2	Reactive Oxygen Species (Oxygen Radicals)IBA 12/2021 - 12/2014
2	dapagliflozinIBA 10/2021 - 01/2017
2	olmesartanIBA 03/2019 - 09/2006
2	Omeprazole (Prilosec)FDA LinkGeneric 03/2019 - 01/2018
2	Famotidine (Pepcid)FDA LinkGeneric 03/2019 - 01/2018
2	Phosphotransferases (Kinase)IBA 01/2018 - 04/2008
2	BenzbromaroneIBA 05/2016 - 09/2011
2	Uricosuric AgentsIBA 05/2016 - 09/2011
2	Uric Acid (Urate)IBA 05/2016 - 09/2011
2	IsoprostanesIBA 05/2016 - 01/2010
2	Glycogen Synthase Kinase 3IBA 07/2015 - 12/2014
2	Endothelin Receptors (Endothelin Receptor)IBA 04/2014 - 03/2008
2	SaltsIBA 04/2014 - 10/2012
2	Desoxycorticosterone Acetate (DOCA)FDA Link 04/2014 - 10/2012
2	Hydroxyproline (4 Hydroxyproline)IBA 01/2014 - 11/2009
2	Isosorbide Dinitrate (Isordil)FDA LinkGeneric 09/2012 - 03/2009
2	Protein Kinase CIBA 04/2012 - 08/2010
2	Estrogen ReceptorsIBA 03/2010 - 04/2002
2	Nitric Oxide (Nitrogen Monoxide)FDA Link 03/2010 - 03/2009
2	mitochondrial K(ATP) channelIBA 06/2009 - 12/2007
2	Hydralazine (Apresoline)FDA LinkGeneric 04/2008 - 07/2005
2	Pinacidil (Pindac)FDA Link 04/2008 - 12/2007
2	Estrogen Receptor AntagonistsIBA 03/2008 - 04/2002
2	Angiotensin Receptor AntagonistsIBA 09/2006 - 08/2005
2	Lactic Acid (Lactate)FDA LinkGeneric 02/2003 - 01/2002
2	LipidsIBA 12/2002 - 07/2002
1	Docosahexaenoic AcidsIBA 01/2022
1	Fatty Acids (Saturated Fatty Acids)IBA 01/2022
1	AMP-Activated Protein KinasesIBA 10/2021
1	Dabigatran FDA Link 01/2021
1	Taurine FDA Link 01/2021
1	AcidsIBA 01/2021
1	N- (1,2,3,5,6,7- hexahydro- S- indacen- 4- ylcarbamoyl)- 4- (2- hydroxy- 2- propanyl)- 2- furansulfonamideIBA 01/2021
1	Vitamin K FDA Link 01/2021
1	pyrrolidine dithiocarbamic acidIBA 01/2021
1	Warfarin (Coumadin)FDA LinkGeneric 01/2021
1	eicosapentaenoic acid ethyl esterIBA 01/2020
1	AntioxidantsIBA 01/2020
1	Proton Pump InhibitorsIBA 03/2019
1	Ascorbic Acid (Vitamin C)FDA LinkGeneric 03/2019

Therapy/Procedure

6	Therapeutics 01/2017 - 07/2002
4	Ligation 04/2008 - 08/2007
3	Transplantation 12/2021 - 01/2017
1	Stem Cell Transplantation 11/2020